Welcome to the Immcantation Portal!
Advances in high-throughput sequencing technologies now allow for large-scale characterization of B cell receptor (BCR) and T cell receptor (TCR) repertoires. The high germline and somatic diversity of the adaptive immune receptor repertoire (AIRR) presents challenges for biologically meaningful analysis - requiring the development of specialized computational methods.
The Immcantation framework provide a start-to-finish analytical ecosystem for high-throughput AIRR-seq datasets. Beginning from raw reads, Python and R packages are provided for pre-processing, population structure determination, and repertoire analysis.
Immcantation supports both the original Change-O standard and the new Adaptive Immune Receptor Repertoire (AIRR) standard developed by the AIRR Community (AIRR-C).
The different tools are available from PyPi, CRAN and Bitbucket. Versioned containers with all tools installed are hosted on Docker Hub.
Core Packages
Click on the images below for more details.
Contributed Packages
Click on the images below for more details.
IgPhyML
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RAbHIT
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RDI
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sumrep
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